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Universitätsklinikum Essen
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International Hepatitis E Symposium 2020

20 - 22 August 2020

Luisenstraße 58/59
10117 Berlin / Germany

C.-Thomas Bock, PhD
H. Wedemeyer, MD


Dear colleagues and friends!

Hepatitis E virus (HEV) infection, a previously neglected infectious disease, came into the focus of scientists just in the last decade. Initially associated with large outbreaks in countries with limited resources, latest studies have proven that HEV infection can also be acquired autochthonously in industrialized regions.

Today, HEV is the most common cause of acute viral hepatitis worldwide. Public health authorities likewise register a dramatic increase of reported cases. Nevertheless, we are still at the beginning of understanding the burden of HEV infections and, no less important, its pathophysiology. We have learned in recent years that HEV can take different transmission routes depending on the genotype by either fecal/oral (HEV-1 or HEV-2) or zoonotic transmission (HEV-3 and HEV-4); however, the underlying mechanisms remain unclear. We have learned that HEV infection will cause not only acute hepatitis E but also can develop to chronic courses in immunocompromised individuals. Furthermore, extrahepatic manifestations are more commonly reported.

Again, the mechanisms responsible for the variety of the clinical manifestations of HEV infections are still poorly characterized. Prevention and treatment options to combat HEV are a challenge since an effective vaccine is still in a queue and the off-label use of ribavirin has its limits. Beside these open questions, more and more emerging data help us to understand HEV infection including its pathophysiology, epidemiology and clinical manifestation. Apparently, multidisciplinary efforts are needed to characterize in detail the impact of HEV on Global Health, One Health, Personalized Health/Clinics and Virology.

We think it‘s time again to exchange new data and discuss recent findings on HEV infection at the “International Hepatitis E symposium 2020” in Berlin. Berlin is the pulsing capital of Germany not only for the young and the young at heart with uncountable bars, pubs and clubs but also for the culture enthusiasts with bordercrossing theaters, operas, the Berlin Philharmonic Orchestra, and museums including the nearby open-air wall museum. Especially in summer and the warm month of August Berlin is a wonderful city to enjoy the atmosphere in one of the many sidewalk cafés or numerous parks and green spaces.

On behalf of the Organizing Team we invite you to join us in Berlin at the “International Hepatitis E Symposium” in August 2020!

Thomas Bock & Heiner Wedemeyer